My game is not really far from the TKA canon, as I'm a huge fan of his works.
The only difference IMKU is that the time span is different, for some reason I am never able to buy several eras of >5000 years that people can remember and talk about it, in my game the second era is "the past" and it could be a past of 1000 years ago.
Regarding adventures, I usually read adventures and use what I like, sometimes just maps and some NPC's. My problem is that after 12 years playing in Jaiman and Emer, the players needed something different, because they know a lot about these areas (Iron Wind, Lorgalis, Eidolon powers, the JA)
I do not use too many house rules, I'm stuck in RM2 with a few variations and we feel comfortable that way, we use fate points to avoid undramatic deaths and some fixes to spells.