Hu.
Seems like I wasn't the only one to have that idea.
Of course, I initially thought to use SM for that, but later on I discovered that using the Contact RPG rules are much more in sync with the Mass Effect style gameplay.
So, no, I haven't done a lot of work.
But think on it - you'll need to do at least five races with skill backgrounds, racial abilites and then you'll need to work on the Biotics and Tech Powers.
I discovered that some things would be easy to adapt, and some quite hard.
But I'm willing to help and even re-visit the SM rules for this, since my project hasn't gone anywhere