The core book covers psychic abilities.
My SM game is set in a developed Sol system, so it is a lot like Serenity politically. I have had no problems with mechanics or coming up with adventures. Rogue seperatist, autonamous corps, terrorist, pirates, espionage of all sorts be it between govt, corps, orbiting cities (which aften are autonimous nations in thier own right). Add in alien artifacts found at scattered sights around the solar system and their are plenty of plot hooks and data to inspire the characters.