However, there may be a bonus for excessive drinking, or at least effects that aren't penalties.
1. First hits the cerebral cortex; more talkative, less inhibited. Easier to interrogate.
2. Then hippocampus. Memory loss and exaggerated emotions. Maybe easier to go into frenzy or perform Power/Adrenal Maneuvers. Ignore a round of stun, ignore a % of hits; still damages you. Ignore minor penalties from crits until you sober up.
3. Cerebellum helps with balance. Lose Agility bonus.
4. Finally, it hits your medula which regulates involuntary functions. Yeah you could die, but it might be easier to feign death. You might not come out of it though.
This does seem similar to RM poison rules.