I was reading some stuff by Monte Cook (Ptolus) and one thing whose concept I find interesting is Chaositech (available as a supplement).
This is something created by a force (the Galchutt) that basically wants to destroy everything, everywhere and is nether magic nor technology. It's powerful but corruptive; using it can turn the user towards chaos and the Galchutt and help them achieve their destructive ends.
Sounds like the sort of thing the Unlife might be into.