What I'd dearly love to see is:
A generic/setting-less version of Cyberspace. Something you could apply to any genere, whether it's space-opera, cyberpunk, post-apocalypse, fantasy, pulp-adventure, horror, etc. It doesn't seem like it should be too hard to remove certain hooks from Cyberspace, and add a few other things in. And, in the same way that Cyberspace has hooks for using it with more advanced things from SpaceMaster (using CS as a sort of SM-Lite), it should have similar hooks for borrowing from RoleMaster.
(and, before anyone says HARP ... I don't think HARP is as light and flexible as Cyberspace; HARP is _lighter_ than Rolemaster, but also goes in a different direction for several things ... whereas Cyberspace is much closer to being a LITE version of RM/SM)