@VladD
I'm not sure what you mean by question/result windows, but probably. e.g., when you attack, you'll get a few events: damage, crit, experience. These come up on the side of the screen much like, say, Civ 5 events come up in the side of the screen every new turn. As soon as you click the button, the event is applied. If it's damage, that damage is dealt to the defender. If it's a crit, the crit window pops up already populated with attacker, defender, crit severity and crit type. Just input a number and it'll look up the crit, then hit the apply button and it'll apply any extra damage/stun/bleed/modifiers etc to the defender which will then automatically be taken into account when that character is used in the future. If a character dies as a result of any of it, another experience event will pop up.
For house rules, the only customizing you can do right now is to make your own weapons, creatures, skills, and races. There is an options screen however which has plenty of room to grow. So far the only options pertain to rules that were used by my GM or by me, so I'm sure there are lots more that could be added. That's part of why I'm asking people to give me ideas for it so I know what kind of other rules people play with. If they're not too far out of scope with the rules they should be a cinch to add.
And yes there are about 100 weapons in there now, just a few of which don't have their table in the database (Mullet, Nodwick, and a couple others).